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 [http://bioinfo.sarang.net/moin/wiki/upload/MammalianMethylTransfer.pdf Mammalian methyltransferases cause genomic DNA methylation..]  [[http://bioinfo.sarang.net/moin/wiki/upload/MammalianMethylTransfer.pdf|Mammalian methyltransferases cause genomic DNA methylation..]]

DnaMethylation [Enzyme]. [DNA] methyltransferase is an [Enzyme] whose function is to catalyze the transfer of methyl groups between molecules, in this case, [DNA].

CpgIsland methylation은 Mammalian의 경우, [Gene] Regulation, [Genome] Stability, Embryonic Development에 관여합니다.


CpgIsland의 경우에도 Methylation과 관련이 있는 것으로 알고 있는데, 구체적으로 Methylation에 대해서는 잘 모르겠네요.. ComputationalModelingOfGeneticAndBioChemicalNetworks 책의 Chap3(p78)에서도 poly(dI/dC)-poly(dI/dC)를 methyl acceptor로서 사용하여 TranscriptionFactor binding site를 찾는다는 내용이 나오는데, 구체적인 내용은 잘 모르겠습니다.

SeeAlso:


CategoryProtein

DnaMethyltransferase (last edited 2013-09-17 07:52:34 by 61)

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