Diff for "Quadruplex" - BioHackersNet

Differences between revisions 2 and 5 (spanning 3 versions)

[DNA] 4중나선 구조. G-Quadruplex

This 3D-structure of [DNA] is formed in the [Telomere] region and inhibit the telemrase. In addition, it has been found in the [Promoter] region of several [Gene]s inclucing OncoGene. Recently, there has been many interests in G-quadruplex stabiling ligands as anti-cancer. When the G-quadruplex is formed,RNA polymerase or telomerase can't move forward and then, the product, transcript or telomere which induces cellular transformation, is not generated.

-  ⇤ ← Revision 2 as of 2005-11-25 15:16:18 → 
  Size: 410
  Editor: 203
  Comment:
+   ← Revision 5 as of 2005-11-26 00:07:14 → ⇥
  Size: 594
  Editor: 168
  Comment:
-Deletions are marked like this.
+Additions are marked like this.
 Line 2:
- This 3D-structure of DNA is formed in the telemere region and inhibit the telemrase.
 In addition,it has been found in the promoter region of several genes inclucing oncogene.
 Recently, there has been many interests in G-quadruplex stabiling ligands as anti-cancer.
+This 3D-structure of [DNA] is formed in the [Telomere] region and inhibit the telemrase. In addition, it has been found in the [Promoter] region of several [Gene]s inclucing OncoGene. Recently, there has been many interests in G-quadruplex stabiling ligands as anti-cancer.
When the G-quadruplex is formed,RNA polymerase or telomerase can't move forward and then, the product, transcript or telomere which induces cellular transformation, is not generated.